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1.
Mechanism of Lamellar Body Formation by Lung Surfactant Protein B.
Mol Cell
; 81(1): 49-66.e8, 2021 01 07.
Article
in English
| MEDLINE | ID: mdl-33242393
2.
Cilia-Associated Oxysterols Activate Smoothened.
Mol Cell
; 72(2): 316-327.e5, 2018 10 18.
Article
in English
| MEDLINE | ID: mdl-30340023
3.
Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.
Proc Natl Acad Sci U S A
; 113(21)2016 May 24.
Article
in English
| MEDLINE | ID: mdl-27162362
4.
Genetic and biochemical definition of the Hedgehog receptor.
Genes Dev
; 24(1): 57-71, 2010 Jan 01.
Article
in English
| MEDLINE | ID: mdl-20048000
5.
Sterol regulation of developmental and oncogenic Hedgehog signaling.
Biochem Pharmacol
; 196: 114647, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34111427
6.
Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.
Cell Rep
; 10(4): 600-15, 2015 Feb 03.
Article
in English
| MEDLINE | ID: mdl-25640182
7.
Simultaneous measurement of smoothened entry into and exit from the primary cilium.
PLoS One
; 9(8): e104070, 2014.
Article
in English
| MEDLINE | ID: mdl-25119726
8.
Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response.
Dev Cell
; 26(4): 346-57, 2013 Aug 26.
Article
in English
| MEDLINE | ID: mdl-23954590
9.
Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells.
J Biol Chem
; 282(12): 8959-68, 2007 Mar 23.
Article
in English
| MEDLINE | ID: mdl-17200122
10.
Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
Mol Cell
; 19(6): 829-40, 2005 Sep 16.
Article
in English
| MEDLINE | ID: mdl-16168377
11.
Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.
J Biol Chem
; 280(26): 25242-9, 2005 Jul 01.
Article
in English
| MEDLINE | ID: mdl-15866869
12.
Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain.
Mol Cell
; 11(1): 25-33, 2003 Jan.
Article
in English
| MEDLINE | ID: mdl-12535518
13.
Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
J Biol Chem
; 279(41): 43136-47, 2004 Oct 08.
Article
in English
| MEDLINE | ID: mdl-15247248
14.
Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
J Biol Chem
; 278(52): 52479-90, 2003 Dec 26.
Article
in English
| MEDLINE | ID: mdl-14563840
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